Drug intelligence / Profile preview

AP232

Development stage
Preclinical
Lead developer
University of Tennessee Health Science Center
01

Overview

AP232: sourced facts only. name: "Here, we report on the development of AP232 that targets the U2 auxiliary homology motif (UHM) of U2AF1, based on our previously reported SF153." [PMID:41089473]; target: "Here, we report on the development of AP232 that targets the U2 auxiliary homology motif (UHM) of U2AF1, based on our previously reported SF153." [PMID:41089473]; developer: "Department of Pharmaceutical Sciences, College of Pharmacy, University of Tennessee Health Science Center, Memphis, Tennessee 38163, United States." [PMID:41089473]; stage: "AP232 exerted anti-leukemia activity, with higher activities observed in cell lines carrying splicing factor mutations." [PMID:41089473]

02

Targets

U2AF1

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