Drug intelligence / Profile preview

apadenoson

Development stage
Preclinical
Lead developer
Bristol Myers Squibb
Modality
Small Molecules
Administration
Intravenous
01

Overview

Apadenoson is a selective adenosine A2A receptor agonist. It is a small molecule drug developed for its anti-inflammatory and immunomodulatory properties, primarily investigated in preclinical and early clinical studies for conditions such as ischemia-reperfusion injury, inflammation, and potentially other diseases where modulation of the adenosine A2A receptor may be beneficial. Apadenoson acts by binding to the adenosine A2A receptor, leading to increased intracellular cAMP levels and subsequent downstream effects that suppress inflammatory responses.

Brand names
Stedivaze
Other names
apadenoson
02

Targets

ADORA2A (Adenosine A₂A Receptor)

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