Drug intelligence / Profile preview

Apetiviton BC

Development stage
Unknown
Lead developer
Cifarma
Modality
Small Molecules
Administration
Oral
01

Overview

Apetiviton BC is an appetite stimulant and vitamin supplement developed by Cifarma Cientifica Farmaceutica. It is a combination product containing cyproheptadine hydrochloride, a first-generation antihistamine with potent antiserotonergic properties, along with a complex of B vitamins (B1, B2, B3, B6) and Vitamin C. The primary mechanism for appetite stimulation is attributed to cyproheptadine's antagonism of serotonin 5-HT2 receptors in the hypothalamus, which are involved in satiety signaling. By blocking these receptors, the drug helps to increase appetite and promote weight gain in patients suffering from inappetence. The included vitamins serve as essential cofactors in energy metabolism and help address potential nutritional deficiencies associated with poor dietary intake. It is typically administered as an oral solution and is used in pediatric, adult, and elderly populations.

Brand names
Apetiviton BC
02

Targets

HTR2C (5-hydroxytryptamine 2C receptor)mAChR (Muscarinic acetylcholine receptors)HTR2A (Serotonin receptor 5-HT2A)HRH1 (Histamine H1 Receptor)

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