Drug intelligence / Profile preview

APH-1502

Development stage
Preclinical
Lead developer
Aphios Pharma
Modality
Nanoparticles → Drug Delivery Systems, Small Molecules
Administration
Oral, Injectable
01

Overview

APH-1502 is a nanoparticle formulation of cannabidiol (CBD) being developed by Aphios Pharma for the treatment of chemotherapy-induced peripheral neuropathic pain (CIPNP). The drug utilizes Aphios' patented SuperFluids Polymer Nanospheres (SFS-PNS) technology to encapsulate CBD in biodegradable polymer nanoparticles, which is designed to enhance bioavailability and provide extended-release properties. APH-1502 targets the CB1 and CB2 cannabinoid receptors to modulate pain signaling, offering a potential non-opioid alternative for managing neuropathic pain with improved control and reduced systemic side effects. It is currently in the preclinical stage of development as part of a pipeline of extended-release cannabinoid nanotherapies.

Other names
APH-1502 CBD nanoparticlesAPH1502 CBD nanoparticlesAPH 1502 CBD nanoparticles
02

Targets

CNR1 (Cannabinoid receptor 1)

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