Drug intelligence / Profile preview

APHD-002

Development stage
Unknown
Lead developer
Aphaia Pharma
Modality
Small Molecules
Administration
Oral
01

Overview

APHD-002 is a distal jejunal-release formulation of dextrose beads developed by Aphaia Pharma for the treatment of obesity and associated weight-related comorbidities. The drug utilizes a specialized delivery system designed to bypass the proximal small intestine and release dextrose specifically in the distal jejunum. This targeted delivery aims to restore endogenous nutrient-sensing signaling pathways and stimulate natural hormone release patterns (such as GLP-1 and PYY) that are often blunted in individuals with obesity. APHD-002 represents a specific dose formulation within Aphaia's pipeline and is currently being evaluated in Phase II clinical trials, sometimes in combination with other compositions to enhance its metabolic effects.

Other names
dextrose beadsdistal jejunal-release dextrose beads

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