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APJ agonist
- Development stage
- Preclinical
- Lead developer
- InSilico Medicine
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
APJ agonist is a small molecule therapeutic program developed by InSilico Medicine for the treatment of obesity and metabolic diseases. The drug acts as an agonist of the APJ receptor (also known as the apelin receptor), a G protein-coupled receptor that plays a critical role in cardiovascular function, fluid homeostasis, and metabolic regulation. By activating the APJ receptor, the compound aims to leverage the beneficial effects of the apelin signaling pathway, which has been linked to improved insulin sensitivity, glucose metabolism, and cardiovascular health. The program was identified and optimized using InSilico Medicine's proprietary AI-driven drug discovery platform and is currently in the preclinical stage of development.
- Other names
- APJ agonistApelin receptor agonistAPJ receptor agonist
02
Targets
APLNR (Apelin receptor)
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