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Apocynum Tablet
- Development stage
- Preclinical
- Lead developer
- Guangdong Peace Pharmaceutical
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Apocynum Tablet is a traditional Chinese medicine (TCM) formulation primarily used for the treatment of hypertension and the prevention of cardiac hypertrophy. Manufactured by Guangdong Peace Pharmaceutical Corp, the tablet is composed of extracts from *Apocynum venetum* (Luo Bu Ma), *Chrysanthemum indicum* (wild chrysanthemum), and *Stephania tetrandra* (Fangchi). Its cardioprotective and antihypertensive effects are attributed to the inhibition of AKT and ERK1/2 phosphorylation signaling pathways. Clinical studies have supported its efficacy and safety profile in managing blood pressure and mitigating cardiac remodeling.
- Brand names
- Apocynum TabletLuo Bu Ma Pian
- Other names
- Apocynum venetum tablet
02
Targets
MAPK3 (Mitogen-activated protein kinase 1)AKT (RAC-alpha serine/threonine-protein kinase)
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