Drug intelligence / Profile preview

Apple

Development stage: Preclinical
Administration: Oral

Overview

Apple is a widely consumed fruit recognized for its nutritional content, including fiber and polyphenols such as Taxifolin/DHQ. It has been investigated for its potential health benefits, including the reduction of serum cholesterol levels, promotion of weight loss through satiety, and improvement of inflammatory and metabolic responses. Additionally, apples can be a source of beneficial probiotics like Bacillus coagulans TCI711.

Other names: Gala apple

Targets

KEAP1 (Kelch-like ECH-associated protein 1)NF-κBTLR2 (Toll-like Receptor 2)TLR4 (Toll-like receptor 4)TNFA (Tumor necrosis factor alpha (soluble))

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