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apple cider vinegar-Western University
- Development stage
- Unknown
- Lead developer
- Western University
- Modality
- Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Small Molecules, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
- Administration
- Oral
01
Overview
apple cider vinegar-Western University refers to an investigational agent consisting of Jamieson Apple Cider Vinegar with Chromium caplets (NPN: 80078433) being evaluated in an Early Phase 1 clinical trial by Western University. The study investigates the supplement's potential to mitigate metabolic complications, such as insulin resistance and bone density loss, in men with metastatic castration-sensitive prostate cancer (mCSPC) who are receiving androgen deprivation therapy (ADT). The active ingredient, acetic acid (acetate), is hypothesized to act as a prebiotic that increases the abundance of the beneficial gut bacterium Akkermansia muciniphila. This shift in the gut microbiome is intended to improve metabolic health and bone integrity, counteracting the side effects of hormonal therapy.
- Brand names
- Jamieson Apple Cider Vinegar with Chromium
- Other names
- acetic acidacetateapple cider vinegar caplets
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