Drug intelligence / Profile preview

apple-cure

Development stage
Preclinical
Modality
Implantable Devices → Device-based Delivery → Drug Delivery Systems, Transdermal Patches → Device-based Delivery → Drug Delivery Systems, Inhalation Devices → Device-based Delivery → Drug Delivery Systems
Administration
Oral
01

Overview

Apple-cure is an effervescent tablet formulated as a combination product containing pectin, niacin, and apple cider vinegar. It is being investigated for its hypolipidemic effects, aiming to improve serum lipid profiles by significantly reducing total cholesterol, triglycerides, and LDL-cholesterol levels, while simultaneously elevating HDL-cholesterol levels. Its mechanism of action is attributed to the synergistic effects of its components, with apple cider vinegar potentially influencing the glycemic index and activating hepatic AMP-activated protein kinase (AMPK), and pectin acting as a dietary fiber that modulates cholesterol metabolism.

02

Targets

ACC (Acetyl-CoA Carboxylase 1)AMPK (Adenosine monophosphate–activated protein kinase)

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