Drug intelligence / Profile preview

apple of sodom extract

Development stage
Unknown
Lead developer
BeC
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Topical, Oral
01

Overview

Apple of sodom extract is a **non-specific botanical extract term** that has been used for more than one plant-derived preparation in the literature and product databases, most notably extracts associated with **Calotropis procera** and, in older anticancer and dermatology contexts, glycoalkaloid-containing extracts associated with **Solanum sodomeum** marketed as **Curaderm**. As a result, it does not denote a single well-defined active pharmaceutical ingredient with a single established mechanism of action. Depending on source material and formulation, reported bioactivities include cytotoxic, anti-inflammatory, antioxidant, antimicrobial, and keratolytic effects, but these effects are driven by complex mixtures of phytochemicals rather than a clearly validated single molecular target. The term is therefore better treated as an ambiguous botanical preparation than as a specific pharmaceutical drug entity.

Brand names
CuradermCuraderm-SO
Other names
apple of sodom extractSolanum sodomeum extractCalotropis procera extract

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