Drug intelligence / Profile preview

AprèsFlex

Development stage
Unknown
Lead developer
Laila Nutraceuticals
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

AprèsFlex is a patented, bioavailability-enhanced extract of Boswellia serrata gum resin standardized to 20% 3-O-acetyl-11-keto-beta-boswellic acid (AKBA), developed to provide rapid and sustained support for joint comfort and mobility[3][2][1][5][7]. The mechanism of action is centered on the inhibition of the enzyme 5-lipoxygenase (5-LOX), which plays a key role in the production of pro-inflammatory leukotrienes such as leukotriene B4[5][6][10][15]. AprèsFlex also inhibits matrix metalloproteinase-3 (MMP-3), which protects collagen in connective tissues[8]. Clinical studies demonstrate efficacy in reducing pain and improving physical function in osteoarthritis within five days of use, with a low daily dose (100 mg) and high safety profile[1][3]. It is used as a standalone ingredient in dietary supplements for joint health, frequently powering consumer brands for rapid, drug-free joint support[1][13].

Brand names
AprèsFlex
Other names
Aflapin
02

Targets

ALOX12 (Arachidonate 12-lipoxygenase, 12S type)MMP3 (Matrix metalloproteinase-3)

Beyond the preview

Go deeper on AprèsFlex.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on AprèsFlex.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call