Drug intelligence / Profile preview

APR-OM32

Development stage
Preclinical
Lead developer
Relief Therapeutics
Modality
Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

APR-OM32 is an investigational amino acid formulation developed by APR Applied Pharma Research for the management of Tyrosinemia (TYR). The product utilizes APR's proprietary Organic Acid Technology (OAT), a delivery platform designed to improve the sensory properties (taste and smell) and the kinetic profile of amino acid absorption. In Tyrosinemia, patients must adhere to a strict diet low in tyrosine and phenylalanine; APR-OM32 provides the necessary amino acids without these precursors. The OAT formulation aims to mask the unpleasant taste and odor of free amino acids while potentially modulating their release to mimic the absorption of natural proteins, which may lead to more stable plasma amino acid levels and improved metabolic control compared to traditional supplements.

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