Drug intelligence / Profile preview

APR-OM34

Development stage
Preclinical
Lead developer
APR Applied Pharma Research
Modality
Small Molecules
Administration
Oral
01

Overview

APR-OM34 is an investigational methionine-free amino acid formulation developed by APR Applied Pharma Research for the management of Homocystinuria (HCU). It utilizes the company's proprietary Organic Acid Technology (OAT), a drug delivery platform designed to optimize the physiological absorption of amino acids. In patients with HCU, who must adhere to a methionine-restricted diet, APR-OM34 provides a specialized amino acid mix that mimics the slow, sustained release of amino acids from natural intact proteins. This controlled-release profile is intended to prevent rapid spikes in blood amino acid levels, potentially improving metabolic control, reducing the frequency of dosing, and enhancing patient compliance compared to traditional amino acid supplements.

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