Drug intelligence / Profile preview

APREBION Kit

Development stage
Unknown
Lead developer
Symbion Life Science
Modality
Small Molecules
Administration
Oral
01

Overview

APREBION Kit is an oral antiemetic medication developed and marketed by Symbion Life Science. It contains aprepitant, a selective, high-affinity antagonist of human substance P/neurokinin-1 (NK1) receptors. Aprepitant works by blocking the binding of substance P, a neuropeptide involved in the emetic reflex, to NK1 receptors in the brain. This inhibition effectively prevents both acute and delayed nausea and vomiting associated with highly and moderately emetogenic chemotherapy (CINV). The APREBION Kit is typically provided as a 3-capsule pack (one 125 mg and two 80 mg capsules) to cover a three-day treatment cycle. In addition to CINV, it is also indicated for the prevention of postoperative nausea and vomiting (PONV) in adults.

Brand names
APREBIONAPREBION Kit
Other names
Aprepitant 125 mg and 80 mg capsules kitAprepitant125 mg and 80 mg capsules kitAprepitant-125 mg and 80 mg capsules kit
02

Targets

TACR1 (Neurokinin‑1 Receptor)

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