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Aprol
- Development stage
- Approved
- Lead developer
- Crystal Genomics
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Aprol is a non-steroidal anti-inflammatory drug (NSAID) containing naproxen sodium as the active ingredient, developed and marketed by Bilim Pharmaceuticals. It is widely utilized for its analgesic, anti-inflammatory, and antipyretic properties. The medication is indicated for the relief of mild to moderate pain and the treatment of chronic inflammatory conditions, including rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, and acute gouty arthritis. Aprol exerts its therapeutic effects by inhibiting the activity of cyclooxygenase enzymes (COX-1 and COX-2), which are essential for the biosynthesis of prostaglandins. By reducing prostaglandin levels, Aprol effectively mitigates the physiological processes that lead to pain, fever, and inflammation.
- Brand names
- AprolAprol Fort
- Other names
- naproxen sodium
02
Targets
PNLIP (Pancreatic triacylglycerol lipase)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)PGHS-1 (Prostaglandin G/H Synthase 1)
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