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Aptamin C
- Development stage
- Preclinical
- Lead developer
- N Therapeutics
- Modality
- RNA Aptamers → RNA Therapeutics → Nucleic Acid Therapeutics, DNA Aptamers → DNA Therapeutics → Nucleic Acid Therapeutics
- Administration
- Oral, Topical
01
Overview
Aptamin C is an innovative single-stranded DNA aptamer (specifically s-DNA Aptamer-2) developed by Nexmos that binds to the reduced form of vitamin C (ascorbic acid) to stabilize it and delay its oxidation. By preventing oxidative degradation, Aptamin C maximizes the antioxidant, anti-inflammatory, and immunomodulatory efficacy of vitamin C. It is developed as a dietary supplement, cosmetic ingredient, and therapeutic agent. In clinical and preclinical studies, Aptamin C has demonstrated efficacy in enhancing natural killer (NK) cell activity, improving skin conditions such as atopic dermatitis and pruritus, and, in combination with vitamin C (as NXP031), providing neuroprotective effects in models of Parkinson's disease, Alzheimer's disease, and vascular dementia.
- Brand names
- Aptamin C
- Other names
- S-Dna Aptamer-2vitamin C-DNA aptamer complexvitamin C-DNA complex
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