aquafilling

Aquafilling is an injectable hydrophilic gel used primarily for soft tissue augmentation in aesthetic and plastic surgery. It consists of 97–98% physiological saline (sodium chloride solution) and 2–3% polyacrylamide or polyamide[1][3]. The product is designed to be biocompatible and chemically inert. Its main indications include breast augmentation, buttock contouring, facial volume restoration, correction of asymmetry or soft tissue defects (such as those resulting from trauma or previous surgeries), and treatment of skin imperfections like stretch marks or scars[3][4]. The mechanism of action is purely physical—providing volume by occupying space within the injected tissues; it does not have a pharmacological effect on biological targets. Aquafilling was introduced in Japan in 2015 and has been widely used in some countries such as South Korea and Turkey for body contouring procedures[1][5]. However, it is not approved by the US Food and Drug Administration (FDA)[2], with increasing reports highlighting concerns about long-term complications including foreign body reactions, delayed infections (including sepsis), migration of the filler material, chronic inflammation, granuloma formation, abscesses, and other adverse events even years after injection[1][2][5].

Brand names

AquafillingAquafillerAquafilling FacelineAquafilling Bodyline

Other names

polyacrylamide hydrogel fillerhydrophilic gel filler