Drug intelligence / Profile preview

aqueous extract of broccoli seed

Development stage
Unknown
Modality
Small Molecules
Administration
Oral, Topical
01

Overview

Aqueous extract of broccoli seed is a dietary supplement and nutraceutical ingredient derived from the seeds of the Brassica oleracea (broccoli) plant, using water-based extraction methods. The primary bioactive components are glucoraphanin (a glucosinolate), myrosinase (an enzyme), and sulforaphane, which is produced when glucoraphanin is converted by myrosinase during digestion[2][1]. Sulforaphane acts as a potent inducer of phase II detoxification enzymes, supports antioxidant defenses via Nrf2 pathway activation, reduces inflammation, and may have anticancer properties[7][8]. The product is used in supplements for cellular health support, detoxification enhancement, anti-inflammatory effects, cardiovascular health improvement, metabolic support in diabetes management, and as an ingredient in cosmetics for its antioxidant properties[4][6][9]. It is not an approved pharmaceutical drug but widely marketed as a dietary supplement or cosmetic ingredient.

Brand names
OncoProtect ESBroq
Other names
broccoli seed aqueous extractBSAEbroccoli sprout/broccoli seed extract supplement
02

Targets

KEAP1 (Kelch-like ECH-associated protein 1)NFE2L2 (Nuclear factor (erythroid-derived 2)-like 2)

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