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Aquiss is a brand name for an oral solution formulation of sertraline hydrochloride, a potent selective serotonin reuptake inhibitor (SSRI). Developed as a 20 mg/mL concentrate, it is indicated for the treatment of various psychiatric conditions, including major depressive disorder (MDD), obsessive-compulsive disorder (OCD), panic disorder, post-traumatic stress disorder (PTSD), and social anxiety disorder. The mechanism of action involves the inhibition of the presynaptic serotonin transporter (SERT), which prevents the reuptake of serotonin (5-HT) into the neuron, thereby increasing the concentration of the neurotransmitter in the synaptic cleft and enhancing serotonergic signaling. This formulation is particularly useful for patients who require liquid medication or precise dose adjustments. It is marketed by Lupin Healthcare.
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