Arcus Biosciences KIT compound 7

Arcus Biosciences KIT compound 7: sourced facts only. name: "Here, we describe a highly selective small-molecule KIT inhibitor (7) that exhibits excellent broad kinome selectivity, with a selectivity score of S(50%) = 0.003." [PMID:42503832]; target: "Here, we describe a highly selective small-molecule KIT inhibitor (7) that exhibits excellent broad kinome selectivity, with a selectivity score of S(50%) = 0.003." [PMID:42503832]; developer: "Arcus Biosciences, Inc. , Hayward, California94545, United States." [PMID:42503832]; modality: "Here, we describe a highly selective small-molecule KIT inhibitor (7) that exhibits excellent broad kinome selectivity, with a selectivity score of S(50%) = 0.003." [PMID:42503832]; stage: "Compound 7 demonstrated promising in vivo therapeutic efficacy in an SCF-driven acute cutaneous anaphylaxis model in rodents." [PMID:42503832]