ARD-1676

ARD-1676: sourced facts only. name: "We report herein the discovery and extensive characterization of ARD-1676, a highly potent and orally efficacious PROTAC degrader of the androgen receptor (AR)." [PMID:37683104]; target: "We report herein the discovery and extensive characterization of ARD-1676, a highly potent and orally efficacious PROTAC degrader of the androgen receptor (AR)." [PMID:37683104]; developer: "Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan 48109, United States." [PMID:37683104]; modality: "We report herein the discovery and extensive characterization of ARD-1676, a highly potent and orally efficacious PROTAC degrader of the androgen receptor (AR)." [PMID:37683104]; stage: "Oral administration of ARD-1676 effectively reduces the level of AR protein in the VCaP tumor tissue in mice and inhibits tumor growth in the VCaP mouse xenograft tumor model without any sign of toxicity." [PMID:37683104]