arginine + glutamine + omega-3 fatty acids

This is a combination of three immunonutrients—arginine, glutamine, and omega-3 fatty acids—used primarily as an enteral nutrition supplement in clinical settings. These nutrients are often included together in specialized medical nutrition formulas designed to support immune function and modulate inflammatory responses during periods of metabolic stress such as surgery or critical illness. Arginine is a conditionally essential amino acid that promotes T lymphocyte proliferation and enhances immune responses through nitric oxide production. Glutamine supports gastrointestinal mucosal integrity, increases lymphocyte counts, and helps prevent bacterial translocation. Omega-3 fatty acids (primarily EPA and DHA) regulate inflammation by modulating cytokine production and increasing natural killer cell activity. This combination has been studied for perioperative nutritional support in patients undergoing major abdominal cancer surgery but has not consistently demonstrated superior immunomodulatory effects compared to standard enteral nutrition[1][2][6]. The mechanism of action involves modulation of immune cell function, enhancement of wound healing processes (via protein synthesis), maintenance of gut barrier integrity, regulation of inflammatory mediators (e.g., cytokines), and improvement in microcirculation.

Other names

arginineglutamineomega-3 fatty acidsomega3 fatty acidsomega 3 fatty acids