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This is a combination of three compounds—arginine, nicotinamide (also known as niacinamide), and niacin (nicotinic acid)—each with distinct biological roles. Arginine is an amino acid that serves as a precursor for nitric oxide, promoting vasodilation and supporting cardiovascular health. Nicotinamide and niacin are both forms of vitamin B3; they function as precursors to NAD/NADP, essential coenzymes in cellular metabolism. Niacin has additional lipid-lowering effects by modulating lipid metabolism through targets such as β-chain ATP synthase, ABCA1, and DGAT2. The combination may be used in dietary supplements aimed at supporting cardiovascular health by improving blood flow (via arginine) and lipid profiles (via niacin/niacinamide), with potential synergistic antioxidant effects[4][5][8].
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