arginine glutamate

Arginine glutamate is a pharmaceutical combination consisting of the amino acids L-arginine and L-glutamic acid, typically administered as a salt. It is primarily indicated for the treatment of hyperammonemia and hepatic encephalopathy associated with chronic liver diseases such as cirrhosis. The drug works through a dual mechanism to detoxify ammonia: L-arginine serves as a critical intermediate in the urea cycle, promoting the conversion of toxic ammonia into urea in the liver, while L-glutamic acid reacts with ammonia to form glutamine via the action of glutamine synthetase, providing an alternative pathway for ammonia removal in the brain and peripheral tissues. Furen Pharmaceutical Group is a prominent developer and manufacturer of this combination in China, where it is widely used in clinical practice for liver-related metabolic disturbances.

Brand names

Arginine Glutamate Injection

Other names

L-Arginine L-glutamateArginine-glutamic acid saltGlutamate arginine