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ARGX-118 is a monoclonal antibody designed to inhibit Galectin-10, a protein that forms Charcot-Leyden crystals involved in airway inflammation and asthma. The drug aims to dissolve these crystals, thereby modulating immune responses and reducing mucus plugging in the respiratory tract. ARGX-118 represents a novel, first-in-class approach under development by argenx in collaboration with VIB for the treatment of disorders such as asthma and chronic airway inflammation. As of the most recent updates, ARGX-118 remains in preclinical development, and no clinical trial approvals or reported adverse events are available[1][3][5][6].
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