Drug intelligence / Profile preview

ARGX-118

Development stage
Preclinical
Lead developer
argenx
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics
Administration
Parenteral
01

Overview

ARGX-118 is a monoclonal antibody designed to inhibit Galectin-10, a protein that forms Charcot-Leyden crystals involved in airway inflammation and asthma. The drug aims to dissolve these crystals, thereby modulating immune responses and reducing mucus plugging in the respiratory tract. ARGX-118 represents a novel, first-in-class approach under development by argenx in collaboration with VIB for the treatment of disorders such as asthma and chronic airway inflammation. As of the most recent updates, ARGX-118 remains in preclinical development, and no clinical trial approvals or reported adverse events are available[1][3][5][6].

Brand names
ARGX-118ARGX118ARGX 118
Other names
ARGX 118ARGX118ARGX-118
02

Targets

LGALS10 (Galectin-10)

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