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Aripiprazole lauroxil is a long-acting injectable atypical antipsychotic used for the treatment of schizophrenia in adults. It is a prodrug of aripiprazole, meaning it is converted in the body to its active form, aripiprazole. The drug acts primarily as a partial agonist at dopamine D2 and serotonin 5-HT1A receptors and as an antagonist at serotonin 5-HT2A receptors. This pharmacological profile helps rebalance dopamine and serotonin activity in the brain, improving symptoms such as delusions, hallucinations, thought disorders, social withdrawal, and emotional flattening associated with schizophrenia. Aripiprazole lauroxil was developed by Alkermes and is administered via intramuscular injection every four to eight weeks[4][5][7].
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