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ARK-E021 is a small molecule drug that was initially developed by VYNE Pharmaceuticals Ltd. for the treatment of skin and musculoskeletal diseases, with its primary indication being acne vulgaris. The drug was formulated as a topical foam and underwent clinical trials to assess its safety and efficacy in subjects with mild to moderate acne vulgaris. Despite reaching Phase 2 clinical development, the global highest R&D status for ARK-E021 is now discontinued, meaning it is no longer being actively developed or marketed[1].
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