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Armolipid Plus
- Development stage
- Unknown
- Lead developer
- Rotta Research
- Modality
- Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules
- Administration
- Oral
01
Overview
Armolipid Plus is a multi-constituent nutraceutical combination designed to improve lipid profiles in patients with mild to moderate dyslipidemia or hypercholesterolemia, particularly those who are statin-intolerant. It contains six active ingredients: red yeast rice extract (providing monacolin K), berberine, policosanols, folic acid, astaxanthin, and coenzyme Q10. Monacolin K acts as a natural HMG-CoA reductase inhibitor, similar to statins, while berberine and policosanols provide complementary lipid-lowering effects through different pathways. Clinical studies, such as the PIN Study, have demonstrated its efficacy in reducing total cholesterol and LDL-C levels.
- Brand names
- Armolipid Plus
- Other names
- ArmoLIPID PLUSArmolipid Plus-L
02
Targets
AMPK (Adenosine monophosphate–activated protein kinase)LDLR (Low-density lipoprotein receptor)ND1 (Mitochondrial electron transport chain complex I)NADH:ubiquinone oxidoreductase subunit familyHMGCR (3-hydroxy-3-methylglutaryl-coenzyme A reductase)
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