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**Armour Thyroid** is an oral natural desiccated thyroid extract derived from porcine thyroid glands and containing both thyroxine and triiodothyronine. It is being studied by AbbVie for **primary hypothyroidism** in a randomized dose-conversion trial versus levothyroxine in patients stabilized on synthetic T4. Pharmacologically, it functions as **thyroid hormone replacement**, with T4 and T3 acting as agonists of thyroid hormone receptors to restore thyroid hormone signaling in hypothyroid patients; this is a hormone replacement product rather than a novel targeted synthetic agent.
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