Drug intelligence / Profile preview

Arnikamed Gel

Development stage
Unknown
Lead developer
Dr. Theiss Naturwaren
Administration
Topical
01

Overview

Arnikamed Gel is a topical herbal medicinal product developed by Dr. Theiss Naturwaren GmbH for the treatment of blunt trauma and accident-related injuries, including bruises (hematomas), sprains (distortions), contusions, and crushing injuries. The active ingredient is a tincture derived from arnica flowers (*Arnica montana*) at a 1:10 extraction ratio using 70% v/v ethanol. Its therapeutic activity is primarily attributed to sesquiterpene lactones, such as helenalin, which exhibit anti-inflammatory properties by inhibiting the NF-kappaB signaling pathway and modulating other inflammatory mediators. The product is available over-the-counter across several European countries under various brand names, including Arnithei and Arnikamed Dolo Gel. It has been evaluated in Phase II clinical studies for local tolerance and sensitization potential.

Brand names
Arnikamed GelArnikamed Dolo GelArnitheiArnikamed gél
Other names
Arnica montana flower tincture gel
02

Targets

NF-κB

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