Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
ARO-MUC5AC
- Development stage
- Unknown
- Lead developer
- Arrowhead Pharmaceuticals
- Modality
- Chemically Modified siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Conjugated siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
- Administration
- Inhalation
01
Overview
ARO-MUC5AC is an investigational RNA interference (RNAi)-based therapeutic designed to reduce the expression of mucin 5AC (MUC5AC), a protein highly upregulated in the airways of patients with asthma and other muco-obstructive lung diseases. By silencing pulmonary epithelial MUC5AC expression, ARO-MUC5AC aims to decrease mucus production, potentially improving airflow and reducing disease exacerbations in conditions such as asthma and chronic obstructive pulmonary disease (COPD). The drug is administered via inhalation as a solution using a nebulizer. It represents a novel approach distinct from current standard-of-care bronchodilators and anti-inflammatory therapies[1][3][8][9].
02
Targets
MUC5AC (Mucin-5AC)
Beyond the preview
Go deeper on ARO-MUC5AC.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on ARO-MUC5AC.