aromatic-turmerone

Aromatic-turmerone is a natural bioactive compound found in the essential oil of *Curcuma longa* (turmeric). It exhibits a range of biological activities, including **anti-inflammatory effects**, **inhibition of microglia activation**, and **promotion of neural stem cell (NSC) proliferation and neuronal differentiation**. Aromatic-turmerone has also demonstrated neuroprotective effects, attenuating neuroinflammation and brain damage in preclinical models, potentially via **inhibition of Toll-like receptor 4-mediated pathways**, Nrf2 activation, and persistent activation of the p38 signaling pathway, which can activate chaperone-mediated autophagy. This compound is of significant interest as a candidate for supportive therapy in neurodegenerative and neuronal inflammatory diseases, and for promoting regeneration after neural injury[1][2][3][4][5][8].

Other names

ar-turmeronearomatic (ar)-turmerone