Drug intelligence / Profile preview

aronia extract + licorice root

Development stage
Unknown
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

**Aronia extract + licorice root** is a combination dietary supplement composed of extracts from aronia berries (typically Aronia melanocarpa) and licorice root (Glycyrrhiza species). Aronia extract is rich in polyphenols, anthocyanins, and possesses antioxidant properties. Licorice root contains diverse bioactive compounds including glycyrrhizin, glabridin, licochalcone A, and flavonoids. The mechanism of action primarily involves synergistic activation of the antioxidant response element (ARE)—a key mediator in cellular defense against oxidative stress. Licorice root extracts are further documented to exhibit anti-inflammatory, antimicrobial, antiviral, and cytoprotective effects. This combination has been investigated as a nutritional supplement to support antioxidant defenses, metabolic health, and possibly assist in weight management or improvement of cardiovascular and metabolic profiles[1][3].

Other names
aronia berry extract + licorice rootaronia melanocarpa extract + glycyrrhiza glabra root extract
02

Targets

Cyp (Cyclophilin family)

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