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ART5900 is a preclinical-stage monoclonal antibody therapeutic being developed by Arialys Therapeutics for the treatment of anti-N-methyl-D-aspartate receptor (anti-NMDAR) autoimmunity. The drug utilizes blood-brain barrier (BBB) penetrant technology to deliver the monoclonal antibody into the central nervous system, where it is designed to target the NMDA receptor and block the pathogenic effects of autoantibodies associated with autoimmune neuropsychiatric disorders.
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