Drug intelligence / Profile preview

Artacent

Development stage
Phase 4
Lead developer
Tides Medical
Administration
Topical
01

Overview

Artacent is a dual-layer amniotic membrane (DLAM) biologic developed by Tides Medical and clinically evaluated by SerenaGroup for the treatment of chronic diabetic foot ulcers. The product is composed of two layers of dehydrated human amniotic membrane, harvested from placentas during planned Caesarean sections, which are cleaned, decellularized, and folded with the stromal sides facing outward. Artacent serves as a biological scaffold that contains essential growth factors intended to induce angiogenesis, stimulate the proliferation of human dermal fibroblasts, and recruit stem cells necessary for wound repair and tissue regeneration. It is FDA-cleared for homologous use under the 361 HCT/P regulatory pathway and is applied topically to debrided, clean, and uninfected wounds.

Brand names
Artacent
Other names
Dual Layer Amniotic MembraneDLAM
02

Targets

FGF (Fibroblast growth factor 6)VEGFA (Vascular endothelial growth factor A)

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