Drug intelligence / Profile preview

artemisia anomala extract

Development stage
Preclinical
Administration
Oral, Topical
01

Overview

Artemisia anomala extract is a botanical extract derived from the herb Artemisia anomala S. Moore, traditionally used in Chinese medicine for the treatment of inflammatory diseases such as enteritis, atopic dermatitis, chronic bronchitis, rheumatism, and hepatitis. Key mechanisms involve inhibition of inflammatory mediators, including downregulation of inducible nitric oxide synthase (iNOS), suppression of pro-inflammatory cytokines (such as IL-1β and IL-6), and inhibition of the nuclear factor-kappa B (NF-κB) and mitogen-activated protein kinase (MAPK) signaling pathways. The extract, especially its ethyl acetate and ethanol fractions, shows pronounced anti-inflammatory and antioxidative activities in vitro and in vivo, potentially making it useful as a functional food ingredient or anti-inflammatory agent. Although widely used in traditional medicine, its efficacy and safety for clinical indications remain to be established through rigorous human trials[3][4][5][6].

Other names
Artemisia anomala S. Moore extractEAAEAFANan-Liu-Ji-Nu extract
02

Targets

NOS2 (Nitric Oxide Synthase 2)IL1B (Interleukin-1 beta)IL-6 (Interleukin 6)NF-κBMEKNLRP3 (Nod-like receptor family pyrin domain-containing protein 3)

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