artemisiae iwayomogii herba ethanol extract

Text_Start **Artemisiae iwayomogii herba ethanol extract** is an ethanol-based extract from the aerial parts (herba) of *Artemisia iwayomogi* (also known as In-jin-ssuk), a species of mugwort used in East Asian traditional medicine. The extract contains a range of active compounds such as scopoletin, isofraxidin, and other phenolic compounds. Mechanistic studies indicate it inhibits growth, migration, and invasion of human hepatocellular carcinoma cells by inducing apoptosis via increased cleaved caspase-3 and PARP, mitochondrial pathway disruption, and suppression of the PI3K/AKT/mTOR signaling pathway[1]. It also acts as a ligand for peroxisome proliferator-activated receptor delta (PPARδ), leading to enhanced fatty acid oxidation and upregulation of associated metabolic genes in skeletal muscle[3]. Animal studies demonstrate effects in reducing diet-induced obesity, improving lipid/glucose metabolism, and decreasing adipogenic and inflammatory gene expression[4]. The ethanol extract demonstrates antimicrobial activity against *Staphylococcus aureus* and *Cutibacterium acnes*, attributed in part to its phenolic components[2]. Text_End

Other names

Artemisia iwayomogi ethanol extractAI ethanol extractIn-jin-ssuk ethanol extract