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Artiforte
- Development stage
- Unknown
- Lead developer
- Navana Pharmaceuticals
- Modality
- Small Molecules
- Administration
- Ophthalmic
01
Overview
Artiforte is a multi-symptom ophthalmic solution developed by Navana Pharmaceuticals for the relief of eye discomfort, redness, and dryness caused by minor eye irritations. It is a fixed-dose combination containing five active ingredients: glycerin, hypromellose, polyethylene glycol 400, tetrahydrozoline hydrochloride, and zinc sulfate. Glycerin, hypromellose, and polyethylene glycol 400 act as lubricants and demulcents that soothe, restore, and protect the ocular surface by stabilizing the tear film. Tetrahydrozoline hydrochloride is a sympathomimetic alpha-adrenergic receptor agonist that induces local vasoconstriction of conjunctival blood vessels, thereby reducing eye redness and congestion. Zinc sulfate serves as an astringent that helps clear mucus and provides mild antiseptic activity. Artiforte is administered topically as eye drops.
- Brand names
- ArtiforteCombofreshWalgreens Multi-Symptom Relief Eye Drops
- Other names
- glycerin + hypromellose + polyethylene glycol + tetrahydrozoline + zinc sulfateglycerin + hypromellose + polyethylene glycol 400 + tetrahydrozoline + zinc sulfateglycerin + hypromellose + polyethylene glycol 400 + tetrahydrozoline hydrochloride + zinc sulfateglycerin + hypromellose + polyethylene glycol 400 + tetrahydrozoline hydrochloride + zinc sulfate monohydrate
02
Targets
ADRA1A (α1A)ADRA1B (α1B)ADRA1D (α1D)ADRA2A (α2A)ADRA2B (α2B)ADRA2C (α2C)
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