Drug intelligence / Profile preview

ARVN901

Development stage
Unknown
Lead developer
ActualEyes
Modality
Cell Therapies
Administration
Ophthalmic
01

Overview

**ARVN901** is Arctic Vision's licensed development code for **AE101**, an investigational, cryopreserved allogeneic corneal endothelial cell product developed by ActualEyes for corneal endothelial disease. It contains cultured human corneal endothelial cells suspended with a Rho-associated kinase inhibitor and is injected into the anterior chamber to repopulate and regenerate dysfunctional corneal endothelium, restoring endothelial barrier and pump function. The program is intended as a less invasive alternative to donor corneal transplantation for conditions including bullous keratopathy and Fuchs endothelial corneal dystrophy. ([arcticvision.com](https://www.arcticvision.com/pipelinedetail?id=5))

Other names
Corneal Endothelial Therapeutic Cell Product
02

Targets

ROCK2 (Rho-associated coiled-coil containing protein kinase 2)ROCK1 (Rho-associated coiled-coil containing protein kinase 1)

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