Drug intelligence / Profile preview

ASA1-OT15

Development stage
Preclinical
Modality
Peptide-Drug Conjugates → Peptide Conjugates → Peptides, Small Molecules
01

Overview

**ASA1-OT15** is an experimental **peptide-drug conjugate** described in preclinical medicinal chemistry research for **glioblastoma**. It consists of the salicylanilide-derived small molecule **ASA1** conjugated through an oxime linkage to an **oligotuftsin carrier peptide** used for glioblastoma-targeting delivery; in the source series, oligotuftsins are described as ligands of **neuropilin receptors** intended to enhance tumor-cell internalization and tissue penetration. In U87 glioblastoma cells, ASA1-OT15 and related conjugates reduced cell viability, and salicylanilide-induced cell death was associated with **autophagy activation**. The compound appears to be a **research-stage academic construct** rather than a clinically developed therapeutic candidate, and no commercial developer, manufacturer, brand name, dosage form, route, or clinical development program was identified from the provided evidence.

02

Targets

NRP (Neuropilin)

Beyond the preview

Go deeper on ASA1-OT15.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on ASA1-OT15.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call