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ASC301

Development stage: Preclinical
Lead developer: Ascle Therapeutics
Modality: CAR-NK Cells → Other Engineered Cells → Adoptive Cell Transfer → Cell Therapies, Lymphokine-Activated Killer Cells → Native Immune Cells → Adoptive Cell Transfer → Cell Therapies

Overview

ASC301 is an investigational allogeneic natural killer (NK) cell therapy developed by Ascle Therapeutics for the treatment of Alzheimer's disease. As part of the company's ASC3xx series targeting neurological conditions, ASC301 leverages the immunomodulatory and potentially neuroprotective properties of NK cells to address neurodegeneration. While the specific molecular targets have not been disclosed, the therapy is designed to utilize allogeneic NK cells to modulate the neuroinflammatory environment associated with Alzheimer's pathology. The program is currently in the preclinical stage of development.

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