Drug intelligence / Profile preview

ASC37i

Development stage
Preclinical
Lead developer
Ascletis Pharma
Modality
Peptides
Administration
Subcutaneous
01

Overview

ASC37i is a once-monthly subcutaneous triple peptide agonist targeting the glucagon-like peptide-1 receptor (GLP-1R), gastric inhibitory polypeptide receptor (GIPR), and glucagon receptor (GCGR). Developed by Ascletis (歌礼生物科技), the drug is currently in the discovery phase for the treatment of obesity. By simultaneously activating these three metabolic pathways, ASC37i aims to provide superior weight loss efficacy and metabolic benefits compared to single or dual agonists. The once-monthly dosing schedule is designed to improve patient compliance and convenience.

Other names
ASC37iASC-37iASC 37i
02

Targets

GIPR (Gastric inhibitory polypeptide receptor)GLP1R (GLP-1R)GCGR (Glucagon receptor)

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