Drug intelligence / Profile preview

ASC37o

Development stage
Preclinical
Lead developer
Ascletis Pharma
Modality
Peptides
Administration
Oral
01

Overview

ASC37o is an orally administered peptide triple agonist targeting the glucagon-like peptide-1 receptor (GLP-1R), glucose-dependent insulinotropic polypeptide receptor (GIPR), and glucagon receptor (GCGR). Developed by Ascletis (歌礼生物科技), the drug is currently in the discovery phase for the treatment of obesity. By simultaneously activating these three metabolic pathways, ASC37o is designed to achieve superior weight loss and metabolic benefits compared to single or dual agonists. The oral peptide formulation aims to provide a more convenient alternative to injectable therapies in the incretin class, potentially improving patient adherence and accessibility.

Other names
ASC37oASC-37oASC 37o
02

Targets

GLP1R (GLP-1R)GCGR (Glucagon receptor)GIPR (Gastric inhibitory polypeptide receptor)

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