Drug intelligence / Profile preview

Ascophyllum nodosum

Development stage
Preclinical
Lead developer
Acadian Seaplants
Modality
Peptides, Small Molecules
Administration
Oral, Topical, Foliar Spray, Soil Drench
01

Overview

Ascophyllum nodosum is a brown macroalga (seaweed) widely utilized in agriculture, animal nutrition, and human health. As a biostimulant, its extracts enhance crop yield and resilience against abiotic stresses like salinity, drought, and heavy metal toxicity by modulating physiological and biochemical pathways, including antioxidant defense and nutrient uptake. In animal health, it is used as a feed additive to mitigate methane emissions in ruminants, improve iodine metabolism in dairy cows, and provide anti-inflammatory benefits (via fucoidans) in conditions like canine chronic inflammatory enteropathy. Its bioactive constituents include sulfated polysaccharides (fucoidans), phlorotannins (polyphenols), and minerals, which exhibit antioxidant, anticoagulant, and prebiotic properties.

Other names
rockweedknotted wrackNorwegian kelpknotted kelpegg wrackAscophyllum nodosum extractseaweed extract
02

Targets

ATIII (Antithrombin III)TYR (Tyrosinase)TNFA (Tumor necrosis factor alpha (soluble))AMY (Pancreatic alpha-amylase)IL15 (Interleukin 15)Sucrase-Isomaltase

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