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ASKG222 is a fusion protein drug candidate developed by AskGene Pharma using its SmartKine platform. It is designed as an interleukin-2 (IL-2) replacement or inhibitor, targeting the IL-2 pathway to modulate immune responses. The primary therapeutic focus for ASKG222 is the treatment of autoimmune diseases and inflammatory conditions. As of the latest updates, it remains in preclinical development and has not yet entered clinical trials in humans[1][2]. The mechanism involves inhibiting or replacing IL-2 activity to potentially reduce aberrant immune activation associated with autoimmune disorders.
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