Drug intelligence / Profile preview

ASP5502

Development stage
Discontinued
Lead developer
Astellas Pharma Global Development, Inc.
Modality
Small Molecules
Administration
Oral
01

Overview

ASP5502 is an investigational small molecule drug developed by Astellas Pharma for the treatment of primary Sjögren's syndrome. It is a first-in-human, orally administered compound currently in Phase 1 clinical trials. The drug was designed using artificial intelligence to target immune homeostasis, with its mechanism of action believed to involve inhibition of STING (Stimulator of Interferon Genes), a key regulator in innate immunity and inflammation. The primary indication under investigation is primary Sjögren's syndrome, an autoimmune disease characterized by dry mouth and eyes due to lymphocytic infiltration of exocrine glands.

Other names
ASP-5502ASP5502ASP 5502
02

Targets

STING (Stimulator of interferon genes protein)

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