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Aspirin (acetylsalicylic acid) is a widely used nonsteroidal anti-inflammatory drug (NSAID) and salicylate that reduces pain (analgesic), fever (antipyretic), and inflammation. It irreversibly inhibits the cyclooxygenase enzymes COX-1 and COX-2 (prostaglandin-endoperoxide synthase 1 and 2), leading to decreased synthesis of prostaglandins and thromboxanes. This mechanism underlies its effects on pain relief and inflammation as well as its antiplatelet action—preventing blood clot formation by inhibiting thromboxane A2 in platelets. Aspirin is approved for use in mild to moderate pain conditions such as headaches or arthritis; it is also used for secondary prevention of cardiovascular events like heart attack or stroke due to its antithrombotic properties[2][3][5][6][8].
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