aspirin + aluminum glycinate + magnesium carbonate

This combination drug consists of **aspirin**, **aluminum glycinate** (also referred to as dihydroxyaluminum aminoacetate), and **magnesium carbonate** ("heavy magnesium carbonate"), formulated to combine the analgesic, antipyretic, anti-inflammatory, and antiplatelet activities of aspirin with the antacid and mucosal protective effects of aluminum glycinate and magnesium carbonate[1][3][4][8][10]. The antacids are intended to mitigate the gastrointestinal irritation commonly associated with aspirin use by neutralizing excess gastric acid and protecting the stomach lining. \nAspirin works by **irreversible inhibition of cyclooxygenase (COX-1 and COX-2) enzymes**, thereby blocking the synthesis of prostaglandins and thromboxanes, leading to its anti-inflammatory, analgesic, antipyretic, and antiplatelet effects. Aluminum glycinate and magnesium carbonate act locally in the stomach to **neutralize gastric acid**, providing relief from dyspepsia and minimizing gastric irritation from aspirin[1][3][4][8][10]. \nThis combination is primarily indicated for mild to moderate pain, fever, inflammation, and prevention of platelet aggregation (such as for cardiovascular risk reduction), especially in patients prone to GI discomfort from aspirin[1][4][8]. \nThe formulation is approved and marketed in certain countries (notably China)[3][10].

Brand names

Kadewei卡德维

Other names

dihydroxyaluminum aminoacetate + heavy magnesium carbonate + aspirin