aspirin + atorvastatin

Aspirin + atorvastatin is a fixed-dose combination of two small molecule drugs used primarily for the prevention of cardiovascular events such as heart attack and stroke. Aspirin acts as an antiplatelet agent by irreversibly inhibiting cyclooxygenase-1 (COX-1), thereby reducing thromboxane A2 production and preventing platelet aggregation. Atorvastatin is a statin that inhibits HMG-CoA reductase to lower cholesterol synthesis in the liver; it reduces low-density lipoprotein (LDL) cholesterol and triglycerides while increasing high-density lipoprotein (HDL) cholesterol. The combination provides additive benefits in reducing vascular inflammation and improving endothelial function beyond monotherapy with either agent alone. It is indicated for patients at high risk of cardiovascular disease or those who have undergone procedures such as coronary artery bypass grafting[4][5][8].

Brand names

Ecosprin AVAztor AspAtorva AspModlip ASGMactor ASPAtorlip-ASPAtorec-ASPLipikind-ASLipicure-ASTonact-ASP

Other names

atorvastatin + aspirin